منابع مشابه
Buschke-Ollendorff syndrome presenting as a painful nodule
BOS: Buschke-Ollendorff syndrome INTRODUCTION First reported in 1928, Buschke-Ollendorff syndrome (BOS) is an autosomal dominant genodermatosis with high penetrance and variable expressivity. It is characterized by skin-colored or yellow smooth papules, plaques, and nodules up to 2 cm consisting of elastomas or collagenomas, known as dermatofibrosis lenticularis disseminata. This syndrome also ...
متن کاملBuschke-Ollendorff syndrome accidentally diagnosed after a left ankle sprain.
A 9-year-old girl was referred to our clinic for evaluation of a spherical sclerotic bone lesion in the distal metaphysis of the left tibia (Figure 1A). The lesion was accidentally found after a routine radiograph for a minor left ankle injury she sustained a week earlier. Physical examination revealed multiple, asymptomatic, symmetrically located skin lesions on either side of the lower back a...
متن کاملBuschke-Ollendorff syndrome: absence of LEMD3 mutation in an affected family.
BACKGROUND Buschke-Ollendorff syndrome (BOS), an autosomal dominant disorder, features small, acquired, asymptomatic, symmetrical foci of osteosclerosis detected radiographically in epimetaphyseal bone (osteopoikilosis) (OPK) together with connective tissue nevi or juvenile elastomas. Heterozygous, loss-of-function, germline mutation in the LEMD3 gene (which encodes an inner nuclear membrane pr...
متن کاملHelen Ollendorff Curth and Curth-Macklin Syndrome
Helen Ollendorff Curth (1899-1982), is one of the pioneers in dermatology. In 1954, she and Madge Thurlow Macklin (1893–1962), an American medical geneticist, reported, a rare congenital genodermatosis that was later known as Curth-Macklin syndrome. This syndrome is a rare autosomal dominant skin disorder characterized by extensive hyperkeratosis and palmo-plantar keratoderma. This report shed ...
متن کاملHelen Ollendorff-Curth: A dermatologist’s lasting legacy
Helen Ollendorff-Curth (Fig. 1) was one of the first female pioneers in academic dermatology and the study of genodermatoses, and her research contributions continue to resonate today. Born in 1899 into a successful Jewish family in Breslau, Germany (now Wroclaw, Poland), she grew up under the guidance of her mother, Paula, a women’s advocate in her own right. Paula was an elected city councilo...
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ژورنال
عنوان ژورنال: Archives of Dermatology
سال: 2010
ISSN: 0003-987X
DOI: 10.1001/archdermatol.2009.320